Nabsolute: A Startup from Chulalongkorn University with Healthcare Product Efficacy-Enhancing Technology
- Industry: Healthcare
- Research Field:Pharmaceuticals
- Product / Service: Hy-NTM Technology, a nano-modified biopolymer, which can be used in healthcare product
Nabsolute’s Story
Founded in 2020 by Puttimon Sribonfha, RPh from SIMSEA CO., LTD and Assistant Professor Dr. Jittima Luckanagul from the Faculty of Pharmaceutical Sciences, Chulalongkorn University, Nabsolute offers Hy-N™ Technology, a nano-modified biopolymer that is revolutionizing the cosmetics and healthcare industries by improving the efficacy and stability of products. Hy-N™ can be used for various treatments, including acne and scars, anti-aging, anti-wrinkle, and whitening. It provides increased stability and efficacy, moisturization, astringent and anti-inflammatory effects, solubility, permeability, cellular uptake, and absorption, and decreased toxicity and side effects.
Nabsolute is a research-oriented company—a spin-off from Chulalongkorn University. Their management team includes biomedical, polymer science, and healthcare business experts. Nabsolute’s CEO RPh Puttimon Sribonfha has more than 10 years of experience in developing and designing cosmetics and pharmaceutical products, combining with the other CEO, Assistant Professor Dr.Jittima Luckanagul’s decades of extensive knowledge and training in nanotechnology, biomedical, and biochemistry, they desire to utilize and innovate technology that can concretely improve human’s life quality. Nabsolute is also supported by Dr.Jittima Luckanagul’s professor, Dr.Qian Wang, from the University of South Carolina (UofSC) where she obtained her Phd training, as the company’s advisor.
With contributions from the other two members of the management team, RPh Dr.Visarut Buranasudja, an expert in toxicology, safety of new substances, and FDA expert consultant as Chief Compliance Officer, and Dr. Vikram Ahuja, an experienced entrepreneur as Chief Financial officer & Growth Hacker, Nabsolute is here to stay and help enrich and even save people’s lives.
Nabsolute has also achieved full registration of Hy-N™ Technology in the United States and the European Union. The technology is endorsed by the Personal Care Products Council (PCPC) in the US and COSING, the European Commission database for information on cosmetic substances and ingredients. Being registered with these esteemed organizations has enabled Nabsolute to market globally and signifies the technology’s safety and effectiveness.
Know the Hero: Hy-N™ Technology
Nabsolute’s main product is Hy-N™ Technology, a structurally nano-modified biopolymer spherical vehicle for active ingredients in pharmaceuticals, dietary supplements, and skincare products. Hy-N™ delivers active ingredients to their destination more quickly and precisely, enhancing their efficacy and reducing toxicity. Other advantages of Hy-N™ include:
- High safety: It is biocompatible and environmentally friendly since it is a derivative of hyaluronic acid found within the human body.
- High versatility: It is compatible with a wide range of active ingredients from small molecule to large molecule like herbal extract, vitamin, protein, chemical to biological active pharmaceutical ingredients in many industries, such as, the whole pharmaceutical industry, cosmetics, dentistry and medical equipment. Hy-N™ is stable in various formulations; o/w, w/o emulsion, or even in formulations containing high amounts of oil. Consequently, there is no concern of breaking lipid bilayer shells in many formulations.
- Easy use: unlike conventional delivery systems that require special equipment and precise process to encapsulate active ingredients, Hy-N™ Technology is auto-forming; so no complex process or equipment is required. Besides, it is soluble in water and a simple stirrer to incorporate with the ingredients.
Moreover, Hy-N™ Technology is proven to be adjuvant for cancer vaccine and treatment such as chemotherapy, and boosting up efficacy of vitamin B, whey protein, moisturizer, anti-aging and anti-inflammatory agents for better living and better healing. - Novelty: they offer a novel form of hyaluronic acid, conventionally in a linear form whereas their Hy-N™ solution is a hyaluronic grafted with pNIPAM, which present in a spherical shape of hyaluronic acid. A spherical shape benefits as a delivery system together with extra functions greater than typical hyaluronic acid. Hy-N™ Solution is hydrophilic colloid with no changes in viscosity and highly stable after incorporating the active ingredients.
- Extra benefits: Hy-N™ solution itself has functional benefits of moisturizing, anti-inflammatory, wound healing, whitening, anti-aging properties.
In summary, Hy-N™ Technology is a delivery system that helps enhance the stability and efficacy of various active ingredients with the functions of moisturizing, anti-inflammatory, wound healing, whitening, and anti-aging properties. In addition, its extrinsic properties from the topical application are anti-inflammation and wound healing as well. Hy-N™ also shows non-irritation and non-sensitization both in-vitro and in a clinical trial on a human patch test and hypoallergenic test.
Next Move of Nabsolute’s Technology: Expanding the Possibilities of Topical Drug Delivery
Nabsolute plans to continuously enhance healthcare product delivery systems by pursuing clearance for Hy-N™ Technology as a topical drug delivery system by 2024. Additionally, Nabsolute expects to expand its product to the food industry by 2025 and to pharmaceutical products in the market by 2028. With its existing projects and other developing research, Nabsolute will benefit Thailand’s healthcare industry and public health, enriching and saving lives while securing its growth as a spin-off startup from Chulalongkorn University.
Nabsolute is currently looking for clients and corporate partners to collaborate with to broaden its cosmeceutical product line and improve its core technology. They are also looking for strategic investors who want to be part of the exciting journey to transform impactful research into an innovation that benefits society and enriches people’s lives.